Letrozole 2.5mg Tablets

Letrozole 2.5mg Tablets contain an active substance called letrozole. It belongs to a group of medicines called aromatase inhibitors. It is a hormonal (or “endocrine”) breast cancer treatment. Growth of breast cancer is frequently stimulated by oestrogens which are female sex hormones. Letrozole reduces the amount of oestrogen by blocking an enzyme (“aromatase”) involved in the production of oestrogens and therefore may block the growth of breast cancer that needs oestrogens to grow. As a consequence tumour cells slow or stop growing and/or spreading to other parts of the body.

Please contact Crescent Pharma should you require any more information.

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Description

Description

Therapeutic Indication for Letrozole 2.5mg Tablets

  • Adjuvant treatment of postmenopausal women with hormone receptor positive invasive early breast cancer.
  • Extended adjuvant treatment of hormone-dependent-invasive breast cancer in postmenopausal women who have received prior standard adjuvant tamoxifen therapy for 5 years.
  • First-line treatment in postmenopausal women with hormone-dependent advanced breast cancer.
  • Advanced breast cancer after relapse or disease progression, in women with natural or artificially induced postmenopausal endocrine status, who have previously been treated with anti-oestrogens.
  • Neo-adjuvant treatment of postmenopausal women with hormone receptor positive, HER-2 negative breast cancer where chemotherapy is not suitable and immediate surgery not indicated.

Efficacy has not been demonstrated in patients with hormone receptor negative breast cancer.

Please contact Crescent Pharma should you require any more information.